Repeat step 2 using a new narcan nasal spray to give another dose in the other nostril. Narcan nasal spray counteracts the lifethreatening effects of an opioid overdose. Naloxone intranasal administration in the prehospital. This naloxone device is a prepackaged, readytouse, plastic unit that is given up the nose. On march 27, 2018, intranasal naloxone spray inns narcan nasal spray was publicly funded through the ontario naloxone program for pharmacies onpp to all eligible recipients. Narcan naloxone hcl nasal spray is used for the treatment of an opioid emergency or a possible opioid overdose. Get emergency medical help right away after giving the first dose of narcan nasal spray, even if the person wakes up. If additional narcan nasal sprays are available, repeat step 2 every 2 to 3 minutes until the person responds or emergency medical help is. This piece provides stepbystep instructions and illustrations on how to use narcan nasal spray. Restrict prescription of narcan nasal spray 2 mg to opioiddependent patients expected to be at risk. In the hospital setting, narcan is typically given through an iv. If additional doses are needed, given in the other nostril. If the person does not respond in 35 minutes, give a second dose of naloxone. About adapt pharma adapt pharma is a privatelyheld company committed to expanding affordable access to narcan naloxone hci nasal spray and to progressing treatment options in the field of addiction.
Administer narcan nasal spray to a person suspected of an opioid overdose with respiratory depression or unresponsiveness as follows. Important safety information narcan nasal spray is contraindicated in patients known to be hypersensitive to naloxone hydrochloride or to any of the other ingredients. Using narcan nasal spray use narcan nasal spray exactly as prescribed by your healthcare provider and as described in the quick start guide. Proper carrying, storage and administration of an narcan nasal spray kit. Administer narcan nasal spray according to the printed instructions on the device label and the. Narcan nasal spray can be administered by a bystander nonhealthcare professional before emergency medical assistance. Funding of naloxone nasal spray kits through the ontario. Narcan nasal spray is safe and effective in children for known or suspected opioid overdose.
Please upload a copy of your standing order or letter of authorization signed by a physician. Do not remove or test the narcan nasal spray until ready to use. Narcan nasal spray contains naloxone hydrochloride. Narcan is a prescription medication that can be given through an iv or as a nasal spray. However, we are unable to grant final approval to your anda at this time because of the patent issue noted below. Each narcan nasal spray has 1 dose and cannot be reused. Narcan nasal spray can be administered by a bystander nonhealthcare professional before emergency medical. It does not require assembly or any specialized medical training and is also the highest concentrated dose of intranasal naloxone currently available. Both narcan nasal spray and evzio are packaged in a carton containing two doses to allow for repeat dosing if needed. Narcan nasal spray is a pure opioid antagonist indicated for emergency use outside of a hospital to reverse known or suspected opioid overdose, as. The current application is a supplemental nda for narcan naloxone hydrochloride nasal spray 2 mg. Narcan naloxone hydrochloride nasal spray is an opioid antagonist indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory andor central nervous system depression. Naloxone narcan nasal spray utah department of health. Call for emergency medical help, evaluate and support.
Adapt pharma, 2015 place person in recovery position lying on their side. This is an important material to include in all narcan kits that participants receive after completing community opioid overdose trainings. Narcan nasal spray may be dosed every 2 to 3 minutes, if available. Important safety information emergent biosolutions. May repeat using a new narcan nasal spray every 23 minutes serious dr.
Remove the narcan nasal spray from the nostril after giving the dose. Narcan nasal spray opioid overdose responseinstructions for adults and children important. Because treatment of suspected opioid overdose must be performed. Safety data sheet narcan naloxone hydrochloride nasal spray sds revision date. Special hazards arising from the substance or mixture hazardous decomposition. Naloxone nasal spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory andor cns depression mechanism of action opioid antagonist that antagonizes opioid effects by competing for the same receptor sites. Push the middle portion of the narcan nasal spray device to spray 4mg of naloxone into one nostril 4. Drug name active ingredients strength dosage formroute marketing status te code rld rs. Remove the naloxone nasal spray from the nostril after giving the dose. Since most accidental overdoses occur in a home setting, it was developed for first responders. Narcan naloxone hcl nasal spray is the first and only fdaapproved nasal form of naloxone for the emergency treatment of a known or suspected opioid overdose. How to use naloxone nasal spray narcan naloxone for opioid.
How to give narcan nasal spray opioid overdose prevention. If breathing does not return to normal or if breathing difficulty resumes, after 23 minutes, give an additional dose of narcan nasal spray using a new device in the alternate nostril. Move the person on their left side after giving narcan nasal spray. May repeat in 23 minutes in opposite nostril if no or minimal breathing and responsiveness, then as needed if doses are available every 23 minutes. See more indication and important safety information. A person who is either currently using opioids or is a past opioid user who is at risk of returning to opioid use, or. Check for signs of an overdose ask and shake will not wake up slow breathing or breathing has stopped. Twist nasal adapter on tip of applicator until tight.
Narcan nasal spray is used to treat an opioid overdose in an emergency situation. Narcan nasal spray is a pure opioid antagonist indicated for emergency use outside of a hospital to reverse known. You and your family members or caregivers should read this patient information leaflet before an. Narcan nasal spray is to be given right away and does not take the place of emergency medical care.
Take purple cap off of naloxone syringe, insert in other side of applicator and twist in until tight. Tilt head back and given spray 4 mg into one nostril. Florida department of children and families office of. Side effects of narcan nasal naloxone hydrochloride nasal. How to use the va intranasal naloxone kit training video. Readminister narcan nasal spray, using a new nasal spray, every 2 to 3 minutes if the patient does not respond or responds and then relapses into respiratory depression. For questions regarding narcan nasal spray distribution, please call 18444narcan 4627226. Hold narcan with your thumb on the bottom of the plunger and your first and middle fingers on either side of the nozzle. Naloxone hcl nasal spray narcan fda approved nasal spray device indications. Narcan nasal spray is a pure opioid antagonist indicated for emergency use outside of a hospital to reverse known or suspected opioid overdose, as manifested by respiratory andor severe central nervous system depression. Opioid overdose responseinstructions for adults and children. Narcan nasal spray 4mg may be distributed to 1 a person at risk of experiencing an opioidrelated.
Food and drug administration 10903 new hampshire avenue silver spring, md 20993 1888infofda 18884636332 contact fda. Use narcan nasal spray naloxone hydrochloride for known or suspected opioid overdose in adults and children. Each narcan nasal spray contains only one dose of medicine. When calling 911, give the address and say the person is not breathing. Give naloxonecall 911 spray naloxone nasal spray into one nostril see page 8 for detailed instructions. Narcan nasal spray at public interest price terms and conditions. Opioid overdose reversal with naloxone narcan, evzio. Hold the narcan nasal spray with your thumb on the bottom of the plunger and your. When administering narcan nasal spray, always be sure to call 911 right away, even if the person wakes up. Narcan nasal spray 4mg is the only fdaapproved, needlefree formulation of naloxone for the emergency treatment of a known or suspected opioid overdose. How to administer narcan nasal spray after administering. Funding of injectable naloxone kits through the onpp will remain unchanged. Administer narcan nasal spray in alternate nostrils with each dose. Narcan naloxone hcl nasal spray is used for the treatment of an opioid emergency or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.
Narcan is a nasal spray used for the emergency treatment of opioid overdose or possible opioid overdose in adults. How to use narcan nasal spray for an opioid overdose gently insert the tip of the nozzle into one nostril, until your. Jun 24, 2019 narcan nasal spray contains naloxone hydrochloride. Narcan nasal spray by waking up to voice or touch, or is not breathing normally within 2 to 3 minutes, administer an additional dose of narcan nasal spray if available continue to administer additional doses of narcan nasal spray every 2 to 3 minutes using a new narcan nasal spray with each dose until emergency medical assistance. Narcan nasal spray is not a substitute for emergency medical care.
Seek emergency medical assistance immediately after initial use, keeping the patient under continued surveillance. If the person is not breathing, do rescue breathing or cpr if you know it. This was developed to be used at home without the need for any medical training. Baker, systemic bioavailability of fluticasone propionate administered as nasal drops and aqueous nasal spray formulations. Extinguishing media as with any fire, use extinguishing media appropriate for primary cause of fire 5. Narcan nasal spray at public interest price terms and conditions the undersigned customer hereby acknowledges and agrees that narcan nasal spray naloxone hcl 4mg the product made available by adapt pharma, inc. Gently insert the tip of the nozzle into either nostril. Check for signs of an overdose ask and shake will not wake up slow breathing or breathing has stopped drowsy or nodding off. Push half of the naloxone 1ml1cc into each nostril. Peel back the tab with the circle to open the narcan nasal spray.
Keep the patient under surveillance or close watch. Hydrochloride nasal spray, 4 mgspray, to be bioequivalent and, therefore, therapeutically equivalent to the reference listed drug rld, narcan nasal spray, 4 mgspray, of adapt pharma operations limited adapt. Naloxone blocks or reverses the effects of opioid medication, including extreme drowsiness, slowed breathing, or loss of consciousness. For more information about narcan nasal spray, go to. Intranasal in naloxone kit will include narcan nasal spray kit. Tilt the persons head back and spray half of the naloxone up one side of the nose 1cc and half up the other side of the nose 1cc. Required reports and documentation relating to the administration of narcan. Narcan nasal spray may be given every 2 to 3 minutes, if available.
Narcan nasal spray efficacy for emergency treatment of opioid. Adapt pharma to customer at the public interest price is conditioned upon customer making the following. In the outpatient setting, or when ems responds to a call for an overdose, a nasal spray is typically used as it does not require an iv to be started before the medication is given. Safety data sheet narcan naloxone hydrochloride nasal spray. Quick start guide what is narcan naloxone nasal spray. Kits containing narcan nasal spray, which can be administered to someone suffering from a drug overdose, have been placed at some 20 public locations throughout elk grove village as part of the villages effort to combat the opioid. Narcan nasal spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory andor central nervous system depression narcan nasal spray is intended for immediate administration as emergency therapy in settings where opioids may be present. Instructions for use how to use narcan nasal spray. Hold the narcan nasal spray with your thumb on the bottom of the plunger and your first and middle fingers on either side of the nozzle. Do not wait more than 5 minutes to give a second dose. Adapt pharma expands program offering free narcan naloxone. The dose can be repeated every 23 minutes until initial response.
Narcan nasal spray 4 mg was approved on november 18, 2015, as a 505b2 application, which cross referenced the efficacy and safety information from narcan, nda 016636. Press the plunger firmly to give the entire dose of naloxone nasal spray. Naloxone for opioid drug overdose how to use naloxone nasal spray narcan step 1. Next, affix the nasal atomizer the soft white piece to the needleless syringe and then assemble the glass cartridge of naloxone see diagram.
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